Quantitative risk assessments underpin most of our federal regulations related to chemicals. Therefore, it is important to understand how and why risk assessments can go astray. Risk assessment brings together concepts of hazard (the potential for a chemical to result in an adverse health outcome, such as carcinogenicity) and exposure. Combining multiple sources of information … Continue reading How and why to close the exposure assessment gap
Tag: Program on Reproductive Health and the Environment
PFAS and chemicals used in plastics associated with increased risk of poor pregnancy outcomes
Chemicals used in plastic production and PFAS are widespread in Bay Area pregnant women and are associated with an increased risk of poor pregnancy outcomes including gestational diabetes, pre-eclampsia, and hypertension, according to UCSF researchers. In a new study published in the July 19, 2023, Environmental Health Perspectives, UCSF researchers with the Program on Reproductive … Continue reading PFAS and chemicals used in plastics associated with increased risk of poor pregnancy outcomes
OMB’s draft Circular A-4 falls short on equity
The Office of Management and Budget (OMB) is currently developing a critical update to its guidance on analysis of benefits and costs of federal regulations, known as Circular A-4. This guidance, which hasn’t been revised since it was issued in 2003, can have a major impact on the extent of public health protections in a … Continue reading OMB’s draft Circular A-4 falls short on equity
CRAs can help EPA more accurately estimate risks from toxic chemical exposures
When a nail salon worker heads home after work, she’s probably carrying more than her paycheck. She is also carrying phthalates — a class of toxic chemicals that contaminates people via nail polish, cosmetics, cleaning supplies, plastics, and food. One nail salon worker is exposed to multiple chemicals from many different sources, yet regulators like … Continue reading CRAs can help EPA more accurately estimate risks from toxic chemical exposures
Makers of PFAS ‘forever chemicals’ covered up the dangers
Widely used in clothing, household products and food, they resist breaking down in the environment The chemical industry took a page out of the tobacco playbook when they discovered and suppressed their knowledge of health harms caused by exposure to PFAS (per- and polyfluoroalkyl substances), according to an analysis of previously secret industry documents by … Continue reading Makers of PFAS ‘forever chemicals’ covered up the dangers
The fox shouldn’t guard the hen house
EPA says it must consider the perspective of multiple stakeholders when regulating, but the chemical industry can play an outsized role in Agency rulemaking. For example, when people paid by industry, through grants, contracts, or as employees, are appointed to EPA scientific advisory committees, this financial conflict of interest (financial COI) can lead to weaker … Continue reading The fox shouldn’t guard the hen house
EPA moves to further limit deadly methylene chloride
EPA today issued a proposed rule that would further limit the deadly chemical methylene chloride, proposing to ban the use of methylene chloride for all consumer uses and most industrial uses. EPA says the banned uses account for 52% of current methylene chloride production. In response, Tracey J. Woodruff, PhD, former EPA senior scientist and … Continue reading EPA moves to further limit deadly methylene chloride
Briefing Capitol Hill on why EPA must use best available science
The PRHE team went to Washington, DC last week to brief lawmakers and policy staff on how EPA can use best available science to improve the way it evaluates chemicals for potential human health harm for the Agency to better protect health, communities, and the environment. Moderated by Tracey J. Woodruff, PhD, MPH, UCSF professor, director … Continue reading Briefing Capitol Hill on why EPA must use best available science
PFAS linked to lower birthweight
The largest study to date to examine the role of PFAS (per- and polyfluoroalkyl substances) in birth outcomes reveals widespread exposure to five PFAS in pregnant women and lower birthweight among those with higher PFAS levels. Published today in the journal Environmental Health Perspectives, the study involved more than 3,000 pregnant participants from 11 different … Continue reading PFAS linked to lower birthweight
Microplastics? More like macro-problem
Take a moment to look at the space you’re in and see just how many plastic items surround you. They might be the container holding the fruit you’re snacking on, the plastic bag with your laundry quarters, or the lid of your water bottle. What you might not see is the plastic you are eating; … Continue reading Microplastics? More like macro-problem











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